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Pinoy Scientist Undertakes Anti-Cancer Research
Written by Loren   
Saturday, 12 February 2011

Lauren Colis, a US-based Filipino scientist and  a post-doctoral fellow at the Department of Radiation Oncology and Molecular Radiation Sciences of the John Hopkins University School of Medicine in Baltimore, Maryland, USA. She had given honor and pride to Filipinos based in Milan when she participated in the 3rd Genomic Instability Workshop. She is a good role model and inspiration to many children of overseas Filipino workers (OFWs). Colis is the only Filipino participant in the 3rd Genomic Instability Workshop held last November 20-23, 2010 at  IFOM-IEO (Firc Institute of Molecular Oncology Foundation-European Institute of Oncology) Campus, in Milan. She joined the other renowned and distinguished scientists from different parts of the world. The workshop is a joint project of GENICA FP7 Health Program, CANGENIN/COST Action BM0703 and NORD FORSK networks and was made feasible in the course of the sponsorship of SEMM (European School of Molecular Medicine), a private foundation for higher education in biomedicine and founded in 2001 by virtue of three decrees from three Italian Ministries (Health, Treasury and University & Research). SEMM promotes and supports research and development undertakings in the emerging sectors of biomedicine like genomics, molecular medicine, nanotechnologies and bioethics. SEMM also supports projects on integration of research and clinical practice.

The goal of the workshop is to provide an avenue for its participants to present and put forward their latest researches and discoveries concerning man’s elusive quest for cancer. Marikki Laiho is the adviser of Colis, they presented the result of their research focusing on identification of the molecular target and anti-tumor activity of 6 novel small molecule compounds activating the p53 pathway (BMH). The study was started in December 2007. The study of the DNA binding properties of BMH and identified the DNA secondary structure is the focus of Colis and Laiho. G-quadruplex (G4-DNA) is used as potential drug target. With their on-going work involving in-vivo experiments to identify protein(s) directly associated with G4 DNA stabilization by BMH, they hope to provide insights on the role of G4 DNA stabilization by BMH to BMH anti-tumor activity. Their work is still in its early stage and continuous research is needed. Colis is confident that their hard work and labor would in some way help if not directly lead to cure cancer. Colis is asking for assistance from big pharmaceutical companies that are directly involved in the development of anti-cancer products. [via abs-cbnnews.com]

 
 


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